Topic by Batavian

  • Batavian
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l currently take Infliximab every 8 weeks for Crohn is Disease. My partner and l are planning to get pregnant while l am feeling well and l was wondering if anyone knows any current facts about the effects of infliximab during pregnancy or can someone give me a link to an updated, genuine site please?!

  Reply by Newman

  • Newman
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How does infliximab affect a baby during pregnancy

Bianca Z,
Infliximab is classed as a ‘biological treatment’ because it has been designed in such a way that it mimics normal human molecules. This drug is used mainly to treat psoriasis, & occasionally to treat rare skin diseases such as pyoderma gangrenosum. It is also widely used in other specialties, for diseases such as rheumatoid arthritis. You should have been informed of the possible side effects of this drug. However, with regard to ur question about the effects of infliximab on pregnancy, u should be aware that giving infliximab is not recommended during pregnancy. Women who may become pregnant must use adequate contraception & continue to use it for at least 6 months after the last infliximab treatment. It is not known whether infliximab comes out in human milk or is absorbed after ingestion. Because special proteins called human immunoglobulins r excreted in the milk, women must not breast feed for at least 6 months after an infliximab treatment. You would be advised to tell ur doctor if u r pregnant or plan to become pregnant. Similarly, if u become pregnant while taking infliximab, tell ur doctor. For obvious reasons, males who r trying to father a child, generally should not receive this drug.




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I add a link with some details of this subject

http://otispregnancy.org/
pdf/infliximab.pdf



Hope this helps
matador 89

  Reply by Norm

  • Norm
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How does infliximab affect a baby during pregnancy

It is classed as 'category C' which means that there is not enough data to give u a proper answer. From what they know how infliximab works, it could harm the baby, they r not 100% sure.

Category C =
''Drugs that, owing to their pharmacological effects, have caused or may be suspected of causing harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible. ''

Basically, u will need to discuss this with the doc. Maybe u can change to a different treatment for the pregnancy or if ur Crohns is mild they might get u to drop it altogether.